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DSST is a neuropsychological test sensitive to brain damage, dementia, age and depression. It isn’t sensitive to the location of brain-damage (except for damage comprising part of the visual field). It consists of (e.g. nine) digit-symbol pairs (e.g. 1/-,2/┴ ... 7/Λ,8/X,9/=) followed by a list of digits. Under each digit the subject should write down the corresponding symbol as fast as possible. The number of correct symbols within the allowed time (e.g. 90 or 120 sec) is measured.

Definition contributed by Anonymous
symbol-digit substitution has been asserted to measure the following CONCEPTS
No concepts assertions have been added.

Phenotypes associated with symbol-digit substitution


No associations have been added.


No associations have been added.


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IMPLEMENTATIONS of symbol-digit substitution
Configurable web-based test paradigm with 9:9 of 8:4 stimulus to key mapping
The DSST was used in the ADNI 1 Cognitive Assessments, which can be downloaded from the link.
EXTERNAL DATASETS for symbol-digit substitution
No implementations have been added.

Experimental conditions are the subsets of an experiment that define the relevant experimental manipulation.


You must specify conditions before you can define contrasts.

In the Cognitive Atlas, we define a contrast as any function over experimental conditions. The simplest contrast is the indicator value for a specific condition; more complex contrasts include linear or nonlinear functions of the indicator across different experimental conditions.

response time

An indicator is a specific quantitative or qualitative variable that is recorded for analysis. These may include behavioral variables (such as response time, accuracy, or other measures of performance) or physiological variables (including genetics, psychophysiology, or brain imaging data).


What can eye movements tell us about Symbol Digit substitution by patients with schizophrenia?
Elahipanah A, Christensen BK, Reingold EM
Schizophrenia research (Schizophr Res)
2011 Apr